What is Camzyos (mavacamten) for?
Buy Camzyos (mavacamten) Online is a selective allosteric and reversible inhibitor of cardiac myosin indicated to treat adults with symptomatic New York Heart Association (NYHA) class II-III obstructive hypertrophic cardiomyopathy (obstructive HCM) to improve functional capacity and symptoms.[1]
It is available in capsule form containing either 2.5 mg, 5 mg, 10 mg, or 15 mg of mavacamten.[1]
How does Camzyos (mavacamten) work?
Hypertrophic cardiomyopathy (HCM) is a disease in which the heart muscle becomes thicker than normal (hypertrophied). The thickened heart muscle becomes stiff, which makes it harder for the heart to pump blood out to the body.[2]
The active ingredient in Buy Camzyos (mavacamten) Online , is an allosteric and reversible inhibitor selective for cardiac myosin. Myosin is a type of protein that is involved in muscle contraction. In HCM patients, this enzyme is excessively active. Camzyos inhibits myosin, which can reduce the symptoms of HCM and improve heart function.[3]
Where has Camzyos (mavacamten) been approved?
Camzyos (mavacamten) was approved by accelerated approval for the treatment of adults with obstructive HCM by:
- The Food and Drug Administration (FDA), USA, on April 28, 2022.[1]
Please note that this medicine may have also been approved in other regions than the ones we’ve listed. If you have a question about its approval in a specific country feel free to contact our support team.
How is Camzyos (mavacamten) taken?
The standard dosage is:[1]
- Starting dose: 5 mg capsule once daily
- Subsequent doses with stepwise increase (titration): 2.5, 5, 10, or 15 mg once daily.
Your clinical status and heart function (left ventricular ejection fraction, LVEF) should be assessed before starting and regularly during treatment so that your dose can be optimised.[1]
Complete information about Buy Camzyos (mavacamten) Online dosage and administration can be found in the official prescribing information listed in our references section.[1]
Note: Please consult with your treating doctor for personalised dosing.
Are there any known adverse reactions or side effects of Camzyos (mavacamten)?
Common adverse reactions
The most common side effects (>5% of patients) listed in the prescribing information include:[1]
- Dizziness
- Fainting (syncope)
Serious adverse reactions
The serious adverse reactions listed in the prescribing information include:[1]
- Heart failure
Use in a specific population
Buy Camzyos (mavacamten) Online may harm your unborn baby when administered to a pregnant woman. Women who can get pregnant should use effective birth control (contraception) during treatment, and for 4 months after their last dose.[1]
Before and during treatment, tell your treating doctor about all the medicines you take. Taking Camzyos with certain medicines or grapefruit juice may cause heart failure. Discuss with your doctor if you are stopping or changing the dose of a medicine or starting a new medicine.[1]
For a comprehensive list of side effects and adverse reactions please refer to the official prescribing information.[1]
References
1. Full prescribing information [FDA]: Camzyos (mavacamten) [PDF]
Novartis, Apr 2022
2. What is Hypertrophic Cardiomyopathy?
Heart.org, cited May 2022
3. U.S. Food and Drug Administration Approves Camzyos™ (mavacamten) for the Treatment of Adults With Symptomatic New York Heart Association Class II-III Obstructive Hypertrophic Cardiomyopathy (HCM) to Improve Functional Capacity and Symptoms
BMS press release, Apr 2022
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